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Aerosol propellants--Toxicology; Fluorocarbons; Ozone-depleting substances


Research results from studies of the physiological effects of aerosal propellants on animals and people are summarized. The papers selected for this summary were published between 1968 and 1975. Effects of the 15 chlorofluorocarbons used as propellants have been recorded on the cardiac, pulmonary and respiratory functions of a number of animal species as well as man. The fifteen propellants have been classified into four groups on the basis of their degree of toxicity. Fluorocarbon 11, the most frequently used propellant, is in group 1, the most toxic. The relative toxicity of each of the 14 other propellants compared with FC 11 is reported. On the basis of these results, it is suggested that the two problems created by chlorofluorocarbon propellants, potential ozone depletion and adverse psychological effects, be considered simultaneously, since limiting the exposure would tend to decrease the risk either to the ozone layer and to people.

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